Bio Processing
Driving Yield, Purity & Process Efficiency Through Membrane Innovation
As the world’s first developer of a membrane for papain concentration (1980), Permionics continues to lead in membrane innovation for complex bioprocesses. Our solutions enable precise separation, high-yield recovery, and scalable purification across fermentation, enzyme extraction, and biotech manufacturing — from lab to commercial scale.
Key Challenges Solved
- Yield loss during traditional chromatography, precipitation, and filtration
- Difficulty isolating sensitive biomolecules from complex mixtures
- High costs and risks with solvent-based purification
- Fouling and inefficiencies in fermentation broth clarification
- Bottlenecks in scaling downstream separation processes
Our Solutions
Permionics offers end-to-end membrane solutions tailored for bioprocessing:
- Ultrafiltration & Diafiltration for high-purity enzyme, protein, and API recovery
- Microfiltration for fermentation broth and herbal extract clarification
- Nanofiltration for organic acid and vitamin concentration
- Stable performance across acidic, alkaline, and solvent-based streams
- Water Recovery from chromatography/SMB column eluents
- Concentration of dilute streams before evaporation
Membrane-Based Bioprocess
Separation Systems
Enhancing process economics and product recovery in enzyme, fermentation, and biomolecule purification.
Applications & Installations
- Triglyceride and fatty acid concentration
- Enzyme purification: cellulases, lipases, peroxidases
- Organic acid recovery: lactic, citric, butyric
- Antibiotics, amino acids, and polysaccharide separations
- Collagen peptide and polymer extraction
- Herbal extracts clarification via MF membranes
Results & Impact
- Higher yield and biomolecule recovery
- Lower energy consumption vs. thermal methods
- Scalable, solvent-minimized purification systems
- Reduced process waste and downtime
- Compliant with cGMP and cleanroom standards
Explore Our High-Performance
Membrane Range
Membrane solutions is dedicated to the development, production, and modification of a variety of microporous filtration membranes.
Chemicals & Petrochemicals
Pharmaceuticals
Pulp & Paper
Power & Energy Generation
Food & Beverage
Textiles & Dyeing
Municipal Water & Wastewater Utilities
Have questions about our products, services, or custom solutions?
Our team is ready to help — let’s connect!
Have questions about our products, services, or custom solutions?
Our team is ready to help — let’s connect!
