System Supplied: Ceramic Microfiltration followed by Two Stage Ultrafiltration automatic PLC system.

Objective: Broth clarification – Separating microbial cells from Enzyme by Microfiltration followed by its concentration & purification by Ultrafiltration/Nanofiltraton.

End-user Sector : Pharmaceutical & Biotech

Process Description & Key Highlights:

  • MF & UF Processes were installed for fermentation broth processing of proteolytic enzyme with fibrinolytic & anti-inflammatory activity commonly used for treating pain and inflammation.
  • MF Ceramic plays role to clarify broth providing cell free clear permeate with > 90-95% enzyme activity recovered for enrichment in next UF process
  • UF Spiral membrane offers dual role as it not only concentrates the enzyme by 30 folds but also purifies it by removing other undesired organic & inorganic broth components.
  • We offer for integrated MF, UF system running continuously along with NF/RO system at the end that processes UF permeate recovering good quality water for reuse.
  • In built process control helps to maintain steady state flux during entire operation completing batch in stipulated time.
Ceramic MF Installation Photo
Ceramic MF Installation Photo
UF Installation Photo
UF Installation Photo